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Abstract hersenontwerp

Emergent Computations in Neural and Behavioural Systems 
DIEP Workshop | 16th September 2026| 9:00 - 17:00 | @De Brug, Roeterseiland campus, Nieuwe Achtergracht 127, Amsterdam

Organizers: Jácome (Jay) Armas, Wout Merbis, Tuan Pham, Clelia de Mulatier, Fernando A.N Santos   

Abstract

Neural and behavioural systems perform sophisticated computations without centralised control. Instead, information processing emerges from the collective dynamics of many interacting, adaptive components. Understanding how these computational capabilities arise from microscopic interactions is a fundamental challenge at the intersection of statistical physics, neuroscience, complex-systems science, and information theory.

This workshop will bring together leading researchers working across theoretical, computational, and experimental approaches to uncover the principles governing emergent computation in distributed and decentralised systems. Particular emphasis will be placed on the connections between the nonequilibrium physics of information processing, adaptation, and learning across multiple scales—from neural circuits and adaptive networks to interacting agents and animal collectives.

By fostering dialogue between communities that often address closely related questions from different perspectives, the workshop aims to develop a shared theoretical language for emergent computation, identify unifying principles, and open new directions for interdisciplinary research.

Confirmed invited speakers 

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Constantino Tsallis
(Brazilian Center for Physics Research)

Professor Constantino Tsallis is a physicist in the area of statistical mechanics, former head of the Department of Theoretical Physics of the Centro Brasileiro de Pesquisas Fisicas, in Rio de Janeiro and also former head of the National Institute of Science and Technology for Complex Systems of Brazil. He has worked in a variety of theoretical subjects in the areas of critical phenomena, chaos and nonlinear dynamics, economics, cognitive psychology, immunology, population evolution, among others. He has focused on entropy and the foundations of statistical mechanics, as well as on some of their scientific and technological applications. In 1988, he proposed a generalization of Boltzmann-Gibbs entropy, which is presently being actively studied around the world.

Professor Iain Couzin is Director of the Max Planck Institute of Animal Behavior and a Professor and Director (Speaker) of the German Research Foundation (DFG) Excellence Cluster “Centre for the Advanced Study of Collective Behaviour” at the University of Konstanz, Germany. His work aims to reveal the principles that underlie evolved collective behavior, and consequently, his research includes the study of a wide range of biological systems, from neural collectives to insect swarms, fish schools, and primate groups.

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Iain Couzin
(Max Planck Institute, University of Konstanz)

Photo_Marianne Bauer

Dr. Marianne Bauer is assistant professor at the Theoretical biophysics and computational biology group of TU Delft. Her work focuses on signal pathways in gene regulation and development, exploring how cells achieve specificity, precision, and plasticity in genetic control. She integrates information theory and signal processing to decode cellular communication, aiming to uncover fundamental principles governing gene expression and developmental decision-making in biological systems.

Marianne Bauer
(TU Delft)

Professor Vijay Balasubramanian is a theoretical physicist and Cathy and Marc Lasry Professor at the University of Pennsylvania focusing on high-energy physics and theoretical biophysics. He is interested in how natural systems manipulate and process information, producing new forms of self-organization. As a biophysicist, he pursues these questions primarily in neuroscience, thinking about the brain as a statistical computational device and seeking to uncover the principles that underlie the organization of neural circuits across scales from cells to the whole brain. 

Vijay_Balasubramanian

Vijay Balasubramanian
(University of Pennsylvania)

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Dr. Fleur Zeldenrust is an Associate Professor at the Neurophysics section at Radboud University, Nijmegen. With a training in both Physics and Neuroscience, she has a broad interest in quantitative solutions to all types of scientific problems, with her expertise being the field of Computational Neuroscience. She and her group study the relationship between the physical properties of the brain and its information processing using a variety of theoretical methods, from (biophysical) neural network modelling to abstract coding models and advanced data analysis of experimental data.

Fleur Zeldenrust
(Radboud University  Nijmegen)

Professor Thierry Mora is a Director of Research at the French National Centre for Scientific Research (CNRS) and the Laboratoire de Physique de l'École Normale Supérieure (LPENS) in Paris. He works at the interface between statistical physics and biology, where he uses mathematical modeling to study complex biological systems. He studies the behaviour of complex biological systems that show interesting  emergent phenomena in immunology, neuroscience, cellular biology, and collective behaviour. He combines a bottom-up approach, in which mechanisms of organisation are hypothesized from efficient design principles, and a top-down approach, where the local rules of interaction are learned from data using statistical learning and statistical physics techniques.
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Theirry Mora
(National Centre for Scientific Research [CNRS])

Schedule and Registration

Practical information

The workshop is a full-day event, taking place from 9:00 until 17:00.

The location of the workshop is De Brug, Roeterseiland campus, Nieuwe Achtergracht 127, Amsterdam.

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Registration:

Please register through this form.

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Tentative shedule:

09:00-09:25: Walk-in

09.25-09.30: Opening remarks

 

09:30-10:15: Speaker 1

10:15-11:00: Speaker 2

11:00-11:30: Coffee break

11:30-12:15: Speaker 3

 

12:15-13:45: Lunch break

 

13:45-14:30: Speaker 4

14:30-15:15: Speaker 5

15:15-15:45: Coffee break

15:45-16:30: Speaker 6

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Professor Constantino Tsallis: Along the Boltzmann-Gibbs-von Neumann-Shannon legacy – Nonadditive entropies


Boltzmann-Gibbs (BG) statistical mechanics is, together with Newton, Einstein and quantum mechanics as 
well as Maxwell electromagnetism, one of the pillars of contemporary theoretical physics. As well known,
this magnificent theory, grounded on the BG additive entropic functional, satisfactorily handles, along more
than 150 years, a plethora of physical phenomena. It fails, however, when relevant space-time correlations
are strictly long-ranged, meaning typically that correlation momenta are not finite at all orders. To overcome
such limitations, a generalized statistical mechanics is possible grounded on nonadditive entropic
functionals. This enlarged theory, first proposed in 1988, has been successfully applied to diverse natural,
technological and social complex systems. Moreover, it implies that the BG entropy is sufficient but not
necessary for preserving the Legendre structure of classical thermodynamics. We will briefly present the
foundations of this generalized theory, as well as applications in low- and high-energy physics, cosmology, granular matter, 
nonlinear dynamical systems, economics, engineering, medical (e.g., EEGs and deep brain microelectrode) and computational sciences, among others.

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Professor Thierry Mora: Modeling correlations in neural and behavioral systems

I will cover two separate topics - collective social behavior in groups of mice, and population coding by retinal neurons - but which both lend themselves to the tools of statistical mechanics to describe how collective behaviour emerges from interactions between individual units. I will describe how to infer these interactions directly from data, and explore their implication for function: for social cohesiveness in social groups, and for visual acuity in the case of retinal coding.

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Dr. Fleur Zeldenrust: From structure to function: Heterogeneity in the brain

 

The brain is a unique system, in that its dynamics have a clear function: making its owner respond to the world around it. In order to perform this function, the brain continuously processes information. How do the dynamics of neurons and networks result in information processing? The physical structure of the brain (its ‘hardware’) shapes this information processing and vice versa: the computations needed for information processing (the ‘software’) are adapted to the physical structure of the hardware. Here, I will discuss this relationship between information processing and neural properties on different levels, from single neurons to networks, and from different perspectives, from single cell electrophysiology to network modelling. In particular, I will focus on heterogeneity: the fact that neurons in the brain are not identical, but show a wide variety of properties. Recently, we showed that this neural diversity itself is not static: it depends on for instance input characteristics and on neuromodulatory state. How does this heterogeneity influence the dynamics and information processing of neural networks? Is this a dial the brain can use to adapt to the requirements of different tasks? I will discuss our latest analysis of experimental data on the heterogeneity of cell properties and how this influences network dynamics and performance in different tasks using different types of network simulations.

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Professor Iain D. Couzin: Ring Attractor Criticality Explains Accurate and Flexible Decision-Making Across Species

As animals run, swim, or fly through the world, they constantly decide where to eat, where to hide, and with whom to associate. Movement both results from these decisions and shapes how options are perceived, represented, and evaluated by changing the spatial relationships among them. I will present an integrated theoretical and experimental framework, grounded in neurobiological principles, that links spatial search and decision-making to ring attractor networks encoding bearings to social and asocial objects. In the absence of salient cues, these networks can occupy distinct search regimes in which excitatory dynamics generate structured trajectories such as zigzags and loops, while inhibitory, noise-driven dynamics generate correlated random walks and run-and-tumble motion, including Lévy-like walks. Cue loss or active inhibition can spontaneously produce spirals and expanding loops as goal-directed activity weakens. Together, these results reveal a reciprocal relationship between neural dynamics and movement. Sufficiently strong, spatially localized cues can instead shift the network into a decision-making regime. As movement changes the geometry of the options, the network resolves multi-option choices through a succession of abrupt, critical binary decisions until only one remains. Using immersive volumetric virtual reality (VR), I will demonstrate this process in fruit flies, ants, desert locusts, and schooling juvenile zebrafish, including decisions involving up to three options and both stationary and moving targets. Theory shows that the mechanism generalizes to any number of options and also predicts that near each critical transition, an animal should become briefly hypersensitive to differences that would otherwise be too small to detect. VR experiments designed to test this prediction reveal that geometric criticality allows animals to be both maximally discriminating and maximally flexible, increasing accuracy while preserving the ability to switch to a better option if conditions change. Finally, I will show how these principles extend to collectives, where individuals act as sensory inputs to one another’s navigational networks, allowing coordinated motion such as fish schooling to emerge directly from those circuits without explicit alignment mechanisms or additional interaction rules.

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Talks

Organisers

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Jácome (Jay) Armas
(University of Amsterdam)

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Wout Merbis
(University of Amsterdam)

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Tuan Pham
(University of Amsterdam)

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Clelia de Mulatier
(University of Amsterdam)

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Fernando A.N Santos
(University of Amsterdam)

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